Ran across a nice case of arteriolar hyalinization in a hypertensive/diabetic patient. This is a 60-ish man with longstanding hypertension and diabetes mellitus II found dead at home. He had a history of increasing weakness and weight loss over the past few months. At autopsy, he had the usual hypertension/diabetes changes, though his kidney was a bit different than what I usually see. His subcapsular scarring wasn’t all that bad, and his arcuate and radial arteries were only middling changed. However, he had pretty impressive hyalinization of his arterioles. The decedent’s vitreous creatinine was 4.4, estimated GFR 12. Here’s some pics. Unfortunately, he was a bit autolyzed, but it’s the thought that counts:
Here’s a side-by-side with a more normal glomerulus from a different case:
As always, free for use with or without attribution, though attribution is always appreciated.




Very nice, Billo. Thanks for sharing
Nice example. His post-mortem changes are on the average to good side of what I often see in my cases.
Sounds like there needs to be some education of LEOs and hospitals in your jurisdiction. It can be hard. I had a case of a double murder/homicide once where I got to the scene at about 8 am, but the cops wouldn’t go into the house without a search warrant, even though you could see two of the bodies through a window. It was summer, and there was no air conditioning in the house.
It was 5 pm by the time the warrant arrived. I spent 8 hours in 90 degree weather staring through a window watching two bodies go from decently preserved to bloated, green and purging. I was not a happy camper.