{"id":586,"date":"2020-10-16T11:47:30","date_gmt":"2020-10-16T15:47:30","guid":{"rendered":"http:\/\/wordpress.forensicpath.us\/?p=586"},"modified":"2023-11-24T21:36:48","modified_gmt":"2023-11-25T02:36:48","slug":"pathology-cases-bacterial-endocarditis","status":"publish","type":"post","link":"https:\/\/wordpress.forensicpath.us\/index.php\/2020\/10\/16\/pathology-cases-bacterial-endocarditis\/","title":{"rendered":"Pathology cases — bacterial endocarditis"},"content":{"rendered":"

This is a repost from the now-defunct Pretty Pics series, with a couple of additions.\u00a0 I don’t remember the actual case any more, but the typical story is that of a young adult intravenous drug abuser with sepsis or some catastrophic failure (stroke, sudden arrhythmia, etc).\u00a0 At autopsy, there is a vegetation (or multiple vegetations) with microabscesses downstream.\u00a0 If the vegetation is on the right, then there’s typically a pneumonia, and if it’s on the left then multiple organs are seeded.\u00a0 In this case, there were microabscesses in multiple organs.<\/p>\n

Grossly, these things look like they sound — sort of amorphous globs on a valve, with some adherent clot.\u00a0 I guess I’ve had about 30 or so of these cases in the past five years.\u00a0 Usually they aren’t all that big when I see them.\u00a0 Here are a couple of gross dissection pics of a couple of ones I’ve seen:<\/p>\n

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Though they can get pretty large.\u00a0 This one sat over a mechanical valve replacement from a previous vegetation:<\/p>\n

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Here’s a typical microscopic appearance of layers of fibrin, inflammatory cells and bacteria:<\/p>\n

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In this case that I made photomics for, there were abscesses in multiple organs, including the heart:<\/p>\n

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The liver:<\/p>\n

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The spleen:<\/p>\n

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The kidney:<\/p>\n

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And the brain:<\/p>\n

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As always, free for use in lecture, or teaching, with or without attribution (though attribution is appreciated).\u00a0 If you put these in a publication, please contact me.\u00a0 Higher resolution images with lossless compression are available on request until I lose them, if you need them for a lecture or such.\u00a0 Email me if you want me to send them to you.<\/p>\n","protected":false},"excerpt":{"rendered":"

This is a repost from the now-defunct Pretty Pics series, with a couple of additions.\u00a0 I don’t remember the actual…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[109,60,1],"tags":[59,76,67,66,56,69,75,25,28,26,77],"class_list":["post-586","post","type-post","status-publish","format-standard","hentry","category-pathology-cases","category-photomicrographs","category-uncategorized","tag-autopsy","tag-bacterial-endocarditis","tag-brain","tag-heart","tag-histology","tag-kidney","tag-liver","tag-microscopy","tag-pathology","tag-photomicrography","tag-vegetation"],"_links":{"self":[{"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/posts\/586","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/comments?post=586"}],"version-history":[{"count":2,"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/posts\/586\/revisions"}],"predecessor-version":[{"id":623,"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/posts\/586\/revisions\/623"}],"wp:attachment":[{"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/media?parent=586"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/categories?post=586"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/tags?post=586"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}