{"id":543,"date":"2020-10-12T10:33:26","date_gmt":"2020-10-12T14:33:26","guid":{"rendered":"http:\/\/wordpress.forensicpath.us\/?p=543"},"modified":"2023-11-24T21:36:48","modified_gmt":"2023-11-25T02:36:48","slug":"pathology-cases-covid-19-pneumonitis","status":"publish","type":"post","link":"https:\/\/wordpress.forensicpath.us\/index.php\/2020\/10\/12\/pathology-cases-covid-19-pneumonitis\/","title":{"rendered":"Pathology cases &#8211; covid-19 pneumonitis"},"content":{"rendered":"<p>Here are some photomicrographs of the lung of a 65-year-old man who came into the hospital short of breath.\u00a0 He tested SARS-Cov-2 positive.\u00a0 His condition deteriorated, complicated by deep vein thrombosis, pulmonary thromboemboli, and cerebrovascular accident.\u00a0 At autopsy, he had, among other things, characteristic lung findings of diffuse alveolar damage with some organization as well as scattered fibrin microthrombi.<\/p>\n<p>Here are some photomics of the lung.<\/p>\n<p>Low power mosaic:<\/p>\n<figure id=\"attachment_553\" aria-describedby=\"caption-attachment-553\" style=\"width: 688px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/covid_low_power_small-scaled.jpg\"><img fetchpriority=\"high\" decoding=\"async\" class=\"size-large wp-image-553\" src=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/covid_low_power_small-1024x530.jpg\" alt=\"\" width=\"688\" height=\"356\" srcset=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/covid_low_power_small-1024x530.jpg 1024w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/covid_low_power_small-300x155.jpg 300w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/covid_low_power_small-768x397.jpg 768w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/covid_low_power_small-1536x795.jpg 1536w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/covid_low_power_small-2048x1059.jpg 2048w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/covid_low_power_small-1600x828.jpg 1600w\" sizes=\"(max-width: 688px) 100vw, 688px\" \/><\/a><figcaption id=\"caption-attachment-553\" class=\"wp-caption-text\">Note that the aveoli are largely obliterated.<\/figcaption><\/figure>\n<p>binary comment<\/p>\n<p>Some closer views of the alevoli, with fibrosis.<\/p>\n<p><a href=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0884-scaled.jpg\"><img decoding=\"async\" class=\"alignnone size-large wp-image-545\" src=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0884-1024x683.jpg\" alt=\"\" width=\"688\" height=\"459\" srcset=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0884-1024x683.jpg 1024w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0884-300x200.jpg 300w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0884-768x512.jpg 768w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0884-1536x1024.jpg 1536w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0884-2048x1365.jpg 2048w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0884-1600x1067.jpg 1600w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0884-272x182.jpg 272w\" sizes=\"(max-width: 688px) 100vw, 688px\" \/><\/a><\/p>\n<p><a href=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0885-scaled.jpg\"><img decoding=\"async\" class=\"size-large wp-image-546\" src=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0885-1024x683.jpg\" alt=\"\" width=\"688\" height=\"459\" srcset=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0885-1024x683.jpg 1024w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0885-300x200.jpg 300w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0885-768x512.jpg 768w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0885-1536x1024.jpg 1536w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0885-2048x1365.jpg 2048w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0885-1600x1067.jpg 1600w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0885-272x182.jpg 272w\" sizes=\"(max-width: 688px) 100vw, 688px\" \/><\/a><\/p>\n<p>Some fibrin in a small vessel:<\/p>\n<p><a href=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0888.TIF.divide-scaled.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-large wp-image-547\" src=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0888.TIF.divide-1024x683.jpg\" alt=\"\" width=\"688\" height=\"459\" srcset=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0888.TIF.divide-1024x683.jpg 1024w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0888.TIF.divide-300x200.jpg 300w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0888.TIF.divide-768x512.jpg 768w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0888.TIF.divide-1536x1024.jpg 1536w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0888.TIF.divide-2048x1365.jpg 2048w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0888.TIF.divide-1600x1067.jpg 1600w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0888.TIF.divide-272x182.jpg 272w\" sizes=\"(max-width: 688px) 100vw, 688px\" \/><\/a><\/p>\n<p>A few more views:<\/p>\n<p><a href=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0890.TIF.divide-scaled.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-large wp-image-548\" src=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0890.TIF.divide-1024x683.jpg\" alt=\"\" width=\"688\" height=\"459\" srcset=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0890.TIF.divide-1024x683.jpg 1024w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0890.TIF.divide-300x200.jpg 300w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0890.TIF.divide-768x512.jpg 768w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0890.TIF.divide-1536x1024.jpg 1536w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0890.TIF.divide-2048x1365.jpg 2048w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0890.TIF.divide-1600x1067.jpg 1600w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0890.TIF.divide-272x182.jpg 272w\" sizes=\"(max-width: 688px) 100vw, 688px\" \/><\/a> <a href=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0892.TIF.divide-scaled.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-large wp-image-549\" src=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0892.TIF.divide-1024x683.jpg\" alt=\"\" width=\"688\" height=\"459\" srcset=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0892.TIF.divide-1024x683.jpg 1024w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0892.TIF.divide-300x200.jpg 300w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0892.TIF.divide-768x512.jpg 768w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0892.TIF.divide-1536x1024.jpg 1536w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0892.TIF.divide-2048x1365.jpg 2048w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0892.TIF.divide-1600x1067.jpg 1600w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0892.TIF.divide-272x182.jpg 272w\" sizes=\"(max-width: 688px) 100vw, 688px\" \/><\/a> <a href=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0894.TIF.divide-scaled.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-large wp-image-550\" src=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0894.TIF.divide-1024x683.jpg\" alt=\"\" width=\"688\" height=\"459\" srcset=\"https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0894.TIF.divide-1024x683.jpg 1024w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0894.TIF.divide-300x200.jpg 300w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0894.TIF.divide-768x512.jpg 768w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0894.TIF.divide-1536x1024.jpg 1536w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0894.TIF.divide-2048x1365.jpg 2048w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0894.TIF.divide-1600x1067.jpg 1600w, https:\/\/wordpress.forensicpath.us\/wp-content\/uploads\/2020\/10\/DSC_0894.TIF.divide-272x182.jpg 272w\" sizes=\"(max-width: 688px) 100vw, 688px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p>As always, free for use in lecture, or teaching, with or without attribution (though attribution is appreciated).\u00a0 If you put these in a publication, please contact me.\u00a0 Higher resolution images with lossless compression are available on request until I lose them, if you need them for a lecture or such. In particular, the whole mount view is about 21Kx11K pixels in the original TIFF image.\u00a0 If you need that big of an image I will have to figure out how to get it to you.\u00a0 Email me if you want me to send them to you.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Here are some photomicrographs of the lung of a 65-year-old man who came into the hospital short of breath.\u00a0 He&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[109,60,1],"tags":[59,36,78,56,65,25,26,74],"class_list":["post-543","post","type-post","status-publish","format-standard","hentry","category-pathology-cases","category-photomicrographs","category-uncategorized","tag-autopsy","tag-covid","tag-diffuse-alveolar-damage","tag-histology","tag-lung","tag-microscopy","tag-photomicrography","tag-pneumonitis"],"_links":{"self":[{"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/posts\/543","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/comments?post=543"}],"version-history":[{"count":3,"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/posts\/543\/revisions"}],"predecessor-version":[{"id":556,"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/posts\/543\/revisions\/556"}],"wp:attachment":[{"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/media?parent=543"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/categories?post=543"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wordpress.forensicpath.us\/index.php\/wp-json\/wp\/v2\/tags?post=543"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}